《爱情手册》系列是意大利大受欢迎的爱情喜剧片，每一集都由四个小故事组成，以群星阵容吸引眼球，第二部更邀请到了好莱坞影星好莱坞老牌影星罗伯特·德尼罗加盟，客串一位离婚后生活在罗马的美国教授。该系列前两部分别在2005年和2007年推出，在本土收获了总计约4500万美元的票房。
经过上一集的惨烈屠杀，汤米（汤姆斯·德科 Thomas Dekker 饰）侥幸和一名女子逃生，然而厄运如影随形，一名衣着考究的神秘男子追踪到了二人暂时栖身的小旅馆，以类似的手法残忍杀害了那名女子，汤米则在此之后下落不明。与此同时，神秘男子投入大笔金钱抢救了徘徊在死亡边缘的面具人（Nick Principe 饰）。苏醒后的面具人更加残暴，在神秘男子的指示下，他将目标锁定在时尚女孩杰丝（蜜米·麦克斯 Mimi Michaels 饰）的身上，一连串新的屠杀再次展开。 另一方面，重案组持续关注近段时间发生的连环杀人案，汤米则成为案件突破的关键。新的屠杀，新的噩梦，在漫漫长夜顾自展开……
麦可(狄恩肯恩饰)在路上搭载了年轻性感的正妹(克莉丝汀波森饰)，麦可原先认为漫漫公路有正妹相伴艳福不浅，自以为遇上了豔遇的他，却不知道自己即将陷入一连串的阴谋及杀机，一趟没有终点的旅程即将展开… 故事描述一个男人在路途中载了一位年轻的女人，原来只是好心借人搭便车，结果男主人公却发现自己陷入了一场可怕的午夜梦魇…… If she looks too good to be true, then she absolutely is. Just ask Michael Anderson (Dean Cain), a gullible film editor who picks up a sexy young hitchhiker (Christie Burson) in the Arizona desert. After the most thrilling one night stand of his life, Michael becomes embroiled in a twisted love con involving a sadistic crime boss (Michael Madsen), a lonely henchman, and a thieving bank manager. Trust isn't just a bitch, it's a dirty little trick! A crime bosss money is missing and he wants it back by any ay means. The beautiful hitchhiker has it and wants to make the getaway. Alexander "Sasha" Shulgin is the scientist behind more than 200 psychedelic compounds - including MDMA, more commonly known as Ecstasy. Considered to be one of the greatest chemists of the 20th century, Sasha's vast array of discoveries have had a profound impact in the field of psychedelic research, making him a subject of fascination and controversy among fellow scientists and a folk hero to recreational users of psychedelics. Dirty Pictures uncovers the lifework of Dr. Shulgin and takes viewers inside his Northern California home where he lives with his wife of 40 years and continues to carry out experiments in a makeshift laboratory. Director étienne Sauret likewise delves into the broader world of psychedelic research - where the fields of chemistry, neuroscience and philosophy intersect - and investigates whether or not this particular field could aid in solving the deepest mysteries of the human mind.
